Increasing concentrations of salt would disrupt lactase activity by disrupting its tertiary structure. This enzyme breaks down lactose.
An enzyme is a protein that acts to lower the activation energy of a given chemical reaction.
Lactase is an enzyme that acts to break down lactose (a disaccharide) into galactose and glucose.
Different conditions in the media (in this case, concentrations of salt) may disrupt enzyme activity by altering its tertiary 3D structure.
Learn more about tertiary protein structure here:
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